Branched-Chain Amino Acids and Di-Alanine Supplementation in Aged Mice: A Translational Study on Sarcopenia

Branched-Chain Amino Acids and Di-Alanine Supplementation in Aged Mice: A Translational Study on Sarcopenia

In age-related sarcopenia, the gradual loss of skeletal muscle mass, function and strength is underpinned by an imbalanced rate of protein synthesis/breakdown. Hence, an adequate protein intake is considered a valuable strategy to mitigate sarcopenia. Here, we investigated the effects of a 12-week o...

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Bibliographic Details
Main Authors: Paola Mantuano, Brigida Boccanegra, Gianluca Bianchini, Ornella Cappellari, Lisamaura Tulimiero, Elena Conte, Santa Cirmi, Francesca Sanarica, Michela De Bellis, Antonietta Mele, Antonella Liantonio, Marcello Allegretti, Andrea Aramini, Annamaria De Luca
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Nutrients
Subjects:
sarcopenia
aging
aged C57BL/6J mice
branched-chain amino acids
L-Alanine
L-Alanyl-L-Alanine
Online Access:https://www.mdpi.com/2072-6643/15/2/330

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https://www.mdpi.com/2072-6643/15/2/330

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