Comparative profiles of lubiprostone, linaclotide, and elobixibat for chronic constipation: a systematic literature review with meta-analysis and number needed to treat/harm

Abstract Objective To comprehensively evaluate the efficacy, safety, patient symptoms, and quality-of-life (QoL) of lubiprostone, linaclotide, and elobixibat as treatment for chronic constipation (CC). Design Systematic literature review (SLR) and meta-analysis (MA). Literature searches were conduct...

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Bibliographic Details
Main Authors: Satish S. Rao, Noriaki Manabe, Yusuke Karasawa, Yuko Hasebe, Kazutaka Nozawa, Atsushi Nakajima, Shin Fukudo
Format: Article
Language:English
Published: BMC 2024-01-01
Series:BMC Gastroenterology
Subjects:
Online Access:https://doi.org/10.1186/s12876-023-03104-8