Identification of the Myogenetic Oligodeoxynucleotides (myoDNs) That Promote Differentiation of Skeletal Muscle Myoblasts by Targeting Nucleolin

Identification of the Myogenetic Oligodeoxynucleotides (myoDNs) That Promote Differentiation of Skeletal Muscle Myoblasts by Targeting Nucleolin

Herein we report that the 18-base telomeric oligodeoxynucleotides (ODNs) designed from the Lactobacillus rhamnosus GG genome promote differentiation of skeletal muscle myoblasts which are myogenic precursor cells. We termed these myogenetic ODNs (myoDNs). The activity of one of the myoDNs, iSN04, wa...

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Bibliographic Details
Main Authors: Sayaka Shinji, Koji Umezawa, Yuma Nihashi, Shunichi Nakamura, Takeshi Shimosato, Tomohide Takaya
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
oligodeoxynucleotide (ODN)
berberine (CID: 12457)
nucleolin (NCL)
skeletal muscle myoblast
myogenic differentiation
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.616706/full

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https://www.frontiersin.org/articles/10.3389/fcell.2020.616706/full

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