Genetic Characteristics Associated With Drug Resistance in Lung Cancer and Colorectal Cancer Using Whole Exome Sequencing of Cell-Free DNA

Genetic Characteristics Associated With Drug Resistance in Lung Cancer and Colorectal Cancer Using Whole Exome Sequencing of Cell-Free DNA

Circulating cell-free DNA (cfDNA) can be used to characterize tumor genomes through next-generation sequencing (NGS)-based approaches. We aim to identify novel genetic alterations associated with drug resistance in lung cancer and colorectal cancer patients who were treated with EGFR-targeted therap...

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Bibliographic Details
Main Authors: Jong Won Lee, Young Soo Park, Jung Yoon Choi, Won Jin Chang, Soohyeon Lee, Jae Sook Sung, Boyeon Kim, Saet Byeol Lee, Sung Yong Lee, Jungmin Choi, Yeul Hong Kim
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Oncology
Subjects:
circulating cell-free DNA (cfDNA)
whole exome sequencing
drug resistance
lung cancer
colorectal cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.843561/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.843561/full

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