Redox stress shortens lifespan through suppression of respiratory complex I in flies with mitonuclear incompatibilities
Incompatibilities between mitochondrial and nuclear genes can perturb respiration, biosynthesis, signaling and gene expression. Here we investigate whether mild mitonuclear incompatibilities alter the physiological response to redox stress induced by N-acetyl cysteine (NAC). We studied three Drosoph...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-05-01
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Series: | Experimental Gerontology |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0531556523000797 |