Redox stress shortens lifespan through suppression of respiratory complex I in flies with mitonuclear incompatibilities

Incompatibilities between mitochondrial and nuclear genes can perturb respiration, biosynthesis, signaling and gene expression. Here we investigate whether mild mitonuclear incompatibilities alter the physiological response to redox stress induced by N-acetyl cysteine (NAC). We studied three Drosoph...

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Bibliographic Details
Main Authors: M. Florencia Camus, Enrique Rodriguez, Vassilios Kotiadis, Hugh Carter, Nick Lane
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:Experimental Gerontology
Online Access:http://www.sciencedirect.com/science/article/pii/S0531556523000797