Oxidized LDL promotes EMS-induced angiogenesis by increasing VEGF-A expression and secretion by endometrial cells

Oxidized LDL promotes EMS-induced angiogenesis by increasing VEGF-A expression and secretion by endometrial cells

Abstract Background Endometriosis (EMS) is a “tumour-like” gynaecological disease with distant metastasis, and studies have shown that EMS can induce distant metastasis through vascular vessels, but the driving factors and their mechanism are not clear. Methods We used an EMS animal model and gene k...

Full description

Bibliographic Details
Main Authors: Caiqi Ma, Wei Huang, Hui Wang, Wenxia Yao, Min Liang, Guifang Yu, Xinke Zhou
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Molecular Medicine
Subjects:
Endometriosis
Vascular metastasis
Angiogenesis
OxLDL
VEGF-A
AKT-HIF-1α signaling
Online Access:https://doi.org/10.1186/s10020-022-00582-6

Internet

https://doi.org/10.1186/s10020-022-00582-6

Similar Items