Single-nucleus RNA sequencing and deep tissue proteomics reveal distinct tumour microenvironment in stage-I and II cervical cancer

Single-nucleus RNA sequencing and deep tissue proteomics reveal distinct tumour microenvironment in stage-I and II cervical cancer

Abstract Background Cervical cancer (CC) is the 3rd most common cancer in women and the 4th leading cause of deaths in gynaecological malignancies, yet the exact progression of CC is inconclusive, mainly due to the high complexity of the changing tumour microenvironment (TME) at different stages of...

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Bibliographic Details
Main Authors: Xiaosong Liu, Guoying Ni, Pingping Zhang, Hejie Li, Junjie Li, Bernardo Cavallazzi Sebold, Xiaolian Wu, Guoqiang Chen, Songhua Yuan, Tianfang Wang
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Single-nucleus RNA sequencing
Quantitative proteomics
Tumour microenvironment
Cervical cancer
Macrophage
Collagen
Online Access:https://doi.org/10.1186/s13046-023-02598-0

Internet

https://doi.org/10.1186/s13046-023-02598-0

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