CFTR Modulator Therapies: Potential Impact on Airway Infections in Cystic Fibrosis

CFTR Modulator Therapies: Potential Impact on Airway Infections in Cystic Fibrosis

Cystic Fibrosis (CF) is an autosomal recessive disease caused by mutations in the gene encoding for the Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein, expressed on the apical surface of epithelial cells. CFTR absence/dysfunction results in ion imbalance and airway surface dehydr...

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Bibliographic Details
Main Authors: Francesca Saluzzo, Luca Riberi, Barbara Messore, Nicola Ivan Loré, Irene Esposito, Elisabetta Bignamini, Virginia De Rose
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Cells
Subjects:
cystic fibrosis
CFTR
modulators
infections
airway microbiology
pathogens
Online Access:https://www.mdpi.com/2073-4409/11/7/1243

Internet

https://www.mdpi.com/2073-4409/11/7/1243

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