Multiple receptor tyrosine kinases regulate dengue infection of hepatocytes

Multiple receptor tyrosine kinases regulate dengue infection of hepatocytes

IntroductionDengue is an arboviral disease causing severe illness in over 500,000 people each year. Currently, there is no way to constrain dengue in the clinic. Host kinase regulators of dengue virus (DENV) infection have the potential to be disrupted by existing therapeutics to prevent infection a...

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Bibliographic Details
Main Authors: Natasha M. Bourgeois, Ling Wei, Nhi N. T. Ho, Maxwell L. Neal, Denali Seferos, Tinotenda Tongogara, Fred D. Mast, John D. Aitchison, Alexis Kaushansky
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
dengue (DENV)
kinase signaling
neglected tropical disease
flavivirus
kinase regression
host-pathogen interactions
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2024.1264525/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2024.1264525/full

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