Improving the biophysical properties of anti-ricin single-domain antibodies

Single-domain antibodies (sdAbs) derived from heavy-chain only antibodies produced in camelids are attractive immunoreagents due to their small size, high affinity, and ability to refold and retain binding activity after denaturation. It has been observed that some sdAbs, however, exhibit undesirabl...

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Bibliographic Details
Main Authors: Kendrick B. Turner, Jinny L. Liu, Dan Zabetakis, Audrey Brozozog Lee, George P. Anderson, Ellen R. Goldman
Format: Article
Language:English
Published: Elsevier 2015-06-01
Series:Biotechnology Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2215017X15000041