Improving the biophysical properties of anti-ricin single-domain antibodies
Single-domain antibodies (sdAbs) derived from heavy-chain only antibodies produced in camelids are attractive immunoreagents due to their small size, high affinity, and ability to refold and retain binding activity after denaturation. It has been observed that some sdAbs, however, exhibit undesirabl...
Main Authors: | Kendrick B. Turner, Jinny L. Liu, Dan Zabetakis, Audrey Brozozog Lee, George P. Anderson, Ellen R. Goldman |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2015-06-01
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Series: | Biotechnology Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2215017X15000041 |
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