HIRA vs. DAXX: the two axes shaping the histone H3.3 landscape

Abstract H3.3, the most common replacement variant for histone H3, has emerged as an important player in chromatin dynamics for controlling gene expression and genome integrity. While replicative variants H3.1 and H3.2 are primarily incorporated into nucleosomes during DNA synthesis, H3.3 is under t...

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Bibliographic Details
Main Authors: Jinmi Choi, Taewan Kim, Eun-Jung Cho
Format: Article
Language:English
Published: Nature Publishing Group 2024-02-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-023-01145-3