Senescence, Necrosis, and Apoptosis Govern Circulating Cell-free DNA Release Kinetics

Senescence, Necrosis, and Apoptosis Govern Circulating Cell-free DNA Release Kinetics

Summary: The kinetics of circulating cell-free DNA (cfDNA) release may provide a real-time assessment of induced cell death. However, there is a limited understanding of the underlying biological rationale for cfDNA release following distinct treatments and cell death mechanisms. Here, we uncover a...

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Bibliographic Details
Main Authors: Ariana Rostami, Meghan Lambie, Caberry W. Yu, Vuk Stambolic, John N. Waldron, Scott V. Bratman
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Cell Reports
Subjects:
circulating cell-free DNA
liquid biopsy
treatment monitoring
kinetics
senescence
necrosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720308111

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http://www.sciencedirect.com/science/article/pii/S2211124720308111

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