Solubility enhancement of some poorly soluble drugs by solid dispersion using Ziziphus spina-christi gum polymer

Solubility enhancement of some poorly soluble drugs by solid dispersion using Ziziphus spina-christi gum polymer

A high percentage of marketed drugs suffer from poor water solubility and require an appropriate technique to increase their solubility. This study aims to compare physically modified and unmodified gum polymers extracted from Ziziphus spina-christi fruits as solid dispersion carriers for some drugs...

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Bibliographic Details
Main Authors: Ameen M. Alwossabi, Eltayeb S. Elamin, Elhadi M.M. Ahmed, Mohammed Abdelrahman
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:Saudi Pharmaceutical Journal
Subjects:
Ziziphus spina-christi
Modification of polymer
Ziziphus gum polymer
Poorly water-soluble drugs
Natural polymer
Solid dispersion
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016422001013

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http://www.sciencedirect.com/science/article/pii/S1319016422001013

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