Loss of Ifnar1 in Pancreatic Acinar Cells Ameliorates the Disease Course of Acute Pancreatitis.

Loss of Ifnar1 in Pancreatic Acinar Cells Ameliorates the Disease Course of Acute Pancreatitis.

Type I interferon constitutes an essential component of the combinational therapy against viral disease. Acute pancreatitis is one side effect of type I interferon-based therapy, implying that activation of type I interferon signaling affects the homeostasis and integrity of pancreatic acinar cells....

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Bibliographic Details
Main Authors: Katharina J Miller, Susanne Raulefs, Bo Kong, Katja Steiger, Ivonne Regel, Andreas Gewies, Jörg Kleeff, Christoph W Michalski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4664425?pdf=render

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http://europepmc.org/articles/PMC4664425?pdf=render

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