Integration of Metabolomics and Proteomics in Exploring the Endothelial Dysfunction Mechanism Induced by Serum Exosomes From Diabetic Retinopathy and Diabetic Nephropathy Patients

Integration of Metabolomics and Proteomics in Exploring the Endothelial Dysfunction Mechanism Induced by Serum Exosomes From Diabetic Retinopathy and Diabetic Nephropathy Patients

BackgroundThe prevalence of diabetic microvascular diseases has increased significantly worldwide, the most common of which are diabetic nephropathy (DN) and diabetic retinopathy (DR). Microvascular endothelial cells are thought to be major targets of hyperglycemic damage, while the underlying mecha...

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Bibliographic Details
Main Authors: Jing Yang, Dongwei Liu, Zhangsuo Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Endocrinology
Subjects:
metabolomics
proteomics
exosomes
diabetic nephropathy
diabetic retinopathy
endothelial dysfunction
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.830466/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2022.830466/full

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