The Transcriptional Repressor ZBTB4 Regulates EZH2 Through a MicroRNA-ZBTB4-Specificity Protein Signaling Axis

ZBTB4 is a transcriptional repressor and examination of publically-available microarray data sets demonstrated an inverse relationship in the prognostic value and expression of ZBTB4 and the histone methyltransferase EZH2 in tumors from breast cancer patients. The possibility of functional interacti...

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Bibliographic Details
Main Authors: Won Seok Yang, Gayathri Chadalapaka, Sung-Gook Cho, Syng-ook Lee, Un-Ho Jin, Indira Jutooru, Kwangmin Choi, Yuet-Kin Leung, Shuk-Mei Ho, Stephen Safe, Kyounghyun Kim
Format: Article
Language:English
Published: Elsevier 2014-12-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558614001468