OpiCa1-PEG-PLGA nanomicelles antagonize acute heart failure induced by the cocktail of epinephrine and caffeine

OpiCa1-PEG-PLGA nanomicelles antagonize acute heart failure induced by the cocktail of epinephrine and caffeine

Background: Reducing Ca2+ content in the sarcoplasmic reticulum (SR) through ryanodine receptors (RyRs) by calcin is a potential intervention strategy for the SR Ca2+ overload triggered by β-adrenergic stress in acute heart diseases. Methods: OpiCal-PEG-PLGA nanomicelles were prepared by thin film d...

Full description

Bibliographic Details
Main Authors: Jun Li, Fei Wang, Xinyan Liu, Zhixiao Yang, Xiaoyu Hua, Hongqiao Zhu, Carmen R. Valdivia, Li Xiao, Songyu Gao, Héctor H. Valdivia, Liang Xiao, Jinming Wang
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Materials Today Bio
Subjects:
OpiCa1-PEG-PLGA nanomicelle
Acute heart failure
β-adrenergic stress
RyR2
Ca2+
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006423003198

Internet

http://www.sciencedirect.com/science/article/pii/S2590006423003198

Similar Items