Natural Inhibitors of Snake Venom Metalloendopeptidases: History and Current Challenges

Natural Inhibitors of Snake Venom Metalloendopeptidases: History and Current Challenges

The research on natural snake venom metalloendopeptidase inhibitors (SVMPIs) began in the 18th century with the pioneering work of Fontana on the resistance that vipers exhibited to their own venom. During the past 40 years, SVMPIs have been isolated mainly from the sera of resistant animals, and ch...

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Bibliografski detalji
Glavni autori: Viviane A. Bastos, Francisco Gomes-Neto, Jonas Perales, Ana Gisele C. Neves-Ferreira, Richard H. Valente
Format: Članak
Jezik:English
Izdano: MDPI AG 2016-08-01
Serija:Toxins
Teme:
cross-linking
hydrogen/deuterium exchange
mass spectrometry
metalloendopeptidase inhibitor
modeling
natural immunity
natural resistance
snake venom
structure
therapeutic application
Online pristup:http://www.mdpi.com/2072-6651/8/9/250

Internet

http://www.mdpi.com/2072-6651/8/9/250

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