The Potential Therapeutic Agent Mepacrine Protects Caco-2 Cells against <named-content content-type="genus-species">Clostridium perfringens</named-content> Enterotoxin Action

The Potential Therapeutic Agent Mepacrine Protects Caco-2 Cells against <named-content content-type="genus-species">Clostridium perfringens</named-content> Enterotoxin Action

ABSTRACT Clostridium perfringens enterotoxin (CPE) causes the diarrhea associated with a common bacterial food poisoning and many antibiotic-associated diarrhea cases. The severity of some CPE-mediated disease cases warrants the development of potential therapeutics. A previous study showed that the...

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Bibliographic Details
Main Authors: John C. Freedman, Matthew R. Hendricks, Bruce A. McClane
Format: Article
Language:English
Published: American Society for Microbiology 2017-08-01
Series:mSphere
Subjects:
Clostridium perfringens
enterotoxin
mepacrine
pore-forming toxin
quinacrine
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00352-17

Internet

https://journals.asm.org/doi/10.1128/mSphere.00352-17

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