<i>Tg(Δ113p53:cmyc)</i> Transgene Upregulates <i>glut1</i> Expression to Promote Zebrafish Heart Regeneration

The heart switches its main metabolic substrate from glucose to fatty acids shortly after birth, which is one of reasons for the loss of heart regeneration capability in adult mammals. On the contrary, metabolic shifts from oxidative phosphorylation to glucose metabolism promote cardiomyocyte (CM) p...

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Bibliographic Details
Main Authors: Zimu Tang, Kaiyuan Wang, Lijian Lo, Jun Chen
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Journal of Cardiovascular Development and Disease
Subjects:
Online Access:https://www.mdpi.com/2308-3425/10/6/246