<i>Tg(Δ113p53:cmyc)</i> Transgene Upregulates <i>glut1</i> Expression to Promote Zebrafish Heart Regeneration

<i>Tg(Δ113p53:cmyc)</i> Transgene Upregulates <i>glut1</i> Expression to Promote Zebrafish Heart Regeneration

The heart switches its main metabolic substrate from glucose to fatty acids shortly after birth, which is one of reasons for the loss of heart regeneration capability in adult mammals. On the contrary, metabolic shifts from oxidative phosphorylation to glucose metabolism promote cardiomyocyte (CM) p...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Zimu Tang, Kaiyuan Wang, Lijian Lo, Jun Chen
Format: Artykuł
Język:English
Wydane: MDPI AG 2023-06-01
Seria:Journal of Cardiovascular Development and Disease
Hasła przedmiotowe:
heart regeneration
glut1
cmyc
zebrafish
glucose transportation
cardiomyocyte proliferation
Dostęp online:https://www.mdpi.com/2308-3425/10/6/246

Internet

https://www.mdpi.com/2308-3425/10/6/246

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