<i>Tg(Δ113p53:cmyc)</i> Transgene Upregulates <i>glut1</i> Expression to Promote Zebrafish Heart Regeneration

The heart switches its main metabolic substrate from glucose to fatty acids shortly after birth, which is one of reasons for the loss of heart regeneration capability in adult mammals. On the contrary, metabolic shifts from oxidative phosphorylation to glucose metabolism promote cardiomyocyte (CM) p...

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Hlavní autoři: Zimu Tang, Kaiyuan Wang, Lijian Lo, Jun Chen
Médium: Článek
Jazyk:English
Vydáno: MDPI AG 2023-06-01
Edice:Journal of Cardiovascular Development and Disease
Témata:
On-line přístup:https://www.mdpi.com/2308-3425/10/6/246