Deep learning predicts gene expression as an intermediate data modality to identify susceptibility patterns in Mycobacterium tuberculosis infected Diversity Outbred mice

Background: Machine learning sustains successful application to many diagnostic and prognostic problems in computational histopathology. Yet, few efforts have been made to model gene expression from histopathology. This study proposes a methodology which predicts selected gene expression values (mic...

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Bibliographic Details
Main Authors: Thomas E. Tavolara, M.K.K. Niazi, Adam C. Gower, Melanie Ginese, Gillian Beamer, Metin N. Gurcan
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:EBioMedicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S235239642100181X