P2X7 Receptor-Dependent microRNA Expression Profile in the Brain Following Status Epilepticus in Mice

P2X7 Receptor-Dependent microRNA Expression Profile in the Brain Following Status Epilepticus in Mice

The ionotropic ATP-gated P2X7 receptor is an important contributor to inflammatory signaling cascades via the release of Interleukin-1β, as well as having roles in cell death, neuronal plasticity and the release of neurotransmitters. Accordingly, there is interest in targeting the P2X7 receptor for...

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Bibliographic Details
Main Authors: Giorgia Conte, Ngoc T. Nguyen, Mariana Alves, Laura de Diego-Garcia, Aidan Kenny, Annette Nicke, David C. Henshall, Eva M. Jimenez-Mateos, Tobias Engel
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Molecular Neuroscience
Subjects:
purinergic signaling
P2X7 receptor
status epilepticus
hippocampus
microRNA
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2020.00127/full

Internet

https://www.frontiersin.org/article/10.3389/fnmol.2020.00127/full

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