Differences in the transactivation domains of p53 family members: a computational study

<p>Abstract</p> <p>The N terminal transactivation domain of p53 is regulated by ligases and coactivator proteins. The functional conformation of this region appears to be an alpha helix which is necessary for its appropriate interactions with several proteins including MDM2 and p30...

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Bibliographic Details
Main Authors: Beuerman Roger W, Madhumalar Arumugam, Mavinahalli Jagadeesh N, Lane David P, Verma Chandra
Format: Article
Language:English
Published: BMC 2010-02-01
Series:BMC Genomics