Transcriptional control of a collagen deposition and adhesion process that promotes lung adenocarcinoma growth and metastasis
A fibrotic stroma accumulates in advanced cancers, and invasive cancer cells migrate along collagen fibers that facilitate dissemination from the primary tumor. However, the ways in which tumor cells govern these processes remain unclear. Here, we report that the epithelial-mesenchymal transition–ac...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Clinical investigation
2022-01-01
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Series: | JCI Insight |
Subjects: | |
Online Access: | https://doi.org/10.1172/jci.insight.153948 |