Characterization of membrane protein interactions by peptidisc-mediated mass photometry

Summary: Membrane proteins perform numerous critical functions in the cell, making many of them primary drug targets. However, their preference for a lipid environment makes them challenging to study using established solution-based methods. Here, we show that peptidiscs, a recently developed membra...

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Bibliographic Details
Main Authors: John William Young, Emanuel Pfitzner, Raman van Wee, Carla Kirschbaum, Philipp Kukura, Carol V. Robinson
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224000063