Tau isoforms are differentially expressed across the hippocampus in chronic traumatic encephalopathy and Alzheimer’s disease

Tau isoforms are differentially expressed across the hippocampus in chronic traumatic encephalopathy and Alzheimer’s disease

Abstract Chronic traumatic encephalopathy (CTE) is a progressive neurodegenerative disease, characterized by hyperphosphorylated tau, found in individuals with a history of exposure to repetitive head impacts. While the neuropathologic hallmark of CTE is found in the cortex, hippocampal tau has prov...

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Bibliographic Details
Main Authors: Jonathan D. Cherry, Camille D. Esnault, Zachary H. Baucom, Yorghos Tripodis, Bertrand R. Huber, Victor E. Alvarez, Thor D. Stein, Dennis W. Dickson, Ann C. McKee
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Acta Neuropathologica Communications
Subjects:
CTE
AD
Tau isoforms
Hippocampus
3R
4R
Online Access:https://doi.org/10.1186/s40478-021-01189-4

Internet

https://doi.org/10.1186/s40478-021-01189-4

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