Effects of ABCA1 R219K Polymorphism and Serum Lipid Profiles on Mild Cognitive Impairment in Type 2 Diabetes Mellitus

Effects of ABCA1 R219K Polymorphism and Serum Lipid Profiles on Mild Cognitive Impairment in Type 2 Diabetes Mellitus

Background: Accumulated evidence suggests that adverse lipid changes are risk factors for type 2 diabetes mellitus (T2DM) and neurodegenerative disorders. The ATP-binding cassette A1 transporter (ABCA1) gene contributes to both lipid processing and amyloid-β formation and thus shows promise as a bio...

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Bibliographic Details
Main Authors: Rongrong Cai, Jing Han, Jie Sun, Rong Huang, Sai Tian, Yanjue Shen, Shaohua Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Aging Neuroscience
Subjects:
high density lipoprotein cholesterol
ATP-binding cassette A1 transporter
type 2 diabetes mellitus
mild cognitive impairment
memory
Online Access:http://journal.frontiersin.org/article/10.3389/fnagi.2017.00257/full

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http://journal.frontiersin.org/article/10.3389/fnagi.2017.00257/full

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