Impact of the Epigenetically Regulated Hoxa-5 Gene in Neural Differentiation from Human Adipose-Derived Stem Cells

Impact of the Epigenetically Regulated Hoxa-5 Gene in Neural Differentiation from Human Adipose-Derived Stem Cells

Human adipose-derived mesenchymal stem cells (hASCs) may be used in some nervous system pathologies, although obtaining an adequate degree of neuronal differentiation is an important barrier to their applicability. This requires a deep understanding of the expression and epigenetic changes of the mo...

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Bibliographic Details
Main Authors: Rosa Hernández, Cristina Jiménez-Luna, Raúl Ortiz, Fernando Setién, Miguel López, Gloria Perazzoli, Manel Esteller, María Berdasco, Jose Prados, Consolación Melguizo
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Biology
Subjects:
mesenchymal stem cells
neuronal differentiation
epigenetic changes
<i>Hoxa-5</i>
CRISPR/dCas9
Online Access:https://www.mdpi.com/2079-7737/10/8/802

Internet

https://www.mdpi.com/2079-7737/10/8/802

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