Matched related transplantation versus immunosuppressive therapy plus eltrombopag for first-line treatment of severe aplastic anemia: a multicenter, prospective study

Matched related transplantation versus immunosuppressive therapy plus eltrombopag for first-line treatment of severe aplastic anemia: a multicenter, prospective study

Abstract This study prospectively compared the efficacy and safety between matched related donor-hematopoietic stem cell transplantation (MRD-HSCT) (n = 108) and immunosuppressive therapy (IST) plus eltrombopag (EPAG) (IST + EPAG) (n = 104) to determine whether MRD-HSCT was still superior as a front...

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Bibliographic Details
Main Authors: Limin Liu, Meiqing Lei, Rong Fu, Bing Han, Xin Zhao, Rongrong Liu, Yanming Zhang, Wenjing Jiao, Miao Miao, Fengkui Zhang, Liansheng Zhang, Depei Wu
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Journal of Hematology & Oncology
Subjects:
Matched related transplantation
Immunosuppressive therapy
Eltrombopag
Severe aplastic anemia
Online Access:https://doi.org/10.1186/s13045-022-01324-1

Internet

https://doi.org/10.1186/s13045-022-01324-1

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