Protein crystallization: Eluding the bottleneck of X-ray crystallography

To date, X-ray crystallography remains the gold standard for the determination of macromolecular structure and protein substrate interactions. However, the unpredictability of obtaining a protein crystal remains the limiting factor and continues to be the bottleneck in determining protein structures...

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Bibliographic Details
Main Authors: Joshua Holcomb, Nicholas Spellmon, Yingxue Zhang, Maysaa Doughan, Chunying Li, Zhe Yang
Format: Article
Language:English
Published: AIMS Press 2017-09-01
Series:AIMS Biophysics
Subjects:
Online Access:http://www.aimspress.com/biophysics/article/1622/fulltext.html