A deficient immune response to SARS-CoV-2 in the nasopharynx is associated with severe COVID-19 pneumonia

A deficient immune response to SARS-CoV-2 in the nasopharynx is associated with severe COVID-19 pneumonia

Objectives: We analyzed the expression of inflammatory and antiviral genes in the nasopharynx of SARS-CoV-2 infected patients and their association with the severity of COVID-19 pneumonia. Methods: We conducted a cross-sectional study on 223 SARS-CoV-2 infected patients. Clinical data were collected...

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Bibliographic Details
Main Authors: Carlos Pita-Martínez, Felipe Pérez-García, Ana Virseda Berdices, María Martin-Vicente, Lucía Castilla-García, Irene Hervás Fernández, Victoria González Ventosa, María José Muñoz-Gómez, Juan Cuadros-González, Jesús F Bermejo-Martin, Salvador Resino, Isidoro Martínez
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:International Journal of Infectious Diseases
Subjects:
SARS-CoV-2
COVID-19
Pneumonia
Gene expression
Mucosal nasopharynx
Immune response
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971223006239

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http://www.sciencedirect.com/science/article/pii/S1201971223006239

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