A Potential Mechanism of Temozolomide Resistance in Glioma–Ferroptosis

Temozolomide (TMZ) is the first-line chemotherapy drug that has been used to treat glioma for over a decade, but the benefits are limited by half of the treated patients who acquired resistance. Studies have shown that glioma TMZ resistance is a complex process with multiple factors, which has not b...

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Bibliographic Details
Main Authors: Zhifang Hu, Yajing Mi, Huiming Qian, Na Guo, Aili Yan, Yuelin Zhang, Xingchun Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.00897/full