A Beta-mixture model for dimensionality reduction, sample classification and analysis

<p>Abstract</p> <p>Background</p> <p>Patterns of genome-wide methylation vary between tissue types. For example, cancer tissue shows markedly different patterns from those of normal tissue. In this paper we propose a beta-mixture model to describe genome-wide methylatio...

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Bibliographic Details
Main Authors: Orntoft Torben, Lamy Philippe, Andersen Claus L, Oster Bodil, Laurila Kirsti, Yli-Harja Olli, Wiuf Carsten
Format: Article
Language:English
Published: BMC 2011-05-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/12/215