Influences of sterol regulatory element binding protein-1c silencing on glucose production in HepG2 cells treated with free fatty acid

Influences of sterol regulatory element binding protein-1c silencing on glucose production in HepG2 cells treated with free fatty acid

Abstract Background Elevation of exogenous free fatty acid (FFA) level leads to insulin resistance (IR) in liver, IR is manifested by elevated hepatic glucose production. We aim to study whether inhibition of endogenous fatty acid synthesis could decrease hepatic glucose production. Methods Low-pass...

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Bibliographic Details
Main Authors: Xiu-Ping Bai, Feng Dong, Guo-Hua Yang, Lei Zhang
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Lipids in Health and Disease
Subjects:
Glucose production
SREBP-1c silencing
Free fatty acid
HepG2 cells
Online Access:http://link.springer.com/article/10.1186/s12944-019-1026-3

Internet

http://link.springer.com/article/10.1186/s12944-019-1026-3

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