Inhibition of miR-101-3p prevents human aortic valve interstitial cell calcification through regulation of CDH11/SOX9 expression

Inhibition of miR-101-3p prevents human aortic valve interstitial cell calcification through regulation of CDH11/SOX9 expression

Abstract Background Calcific aortic valve disease (CAVD) is the second leading cause of adult heart diseases. The purpose of this study is to investigate whether miR-101-3p plays a role in the human aortic valve interstitial cells (HAVICs) calcification and the underlying mechanisms. Methods Small R...

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Bibliographic Details
Main Authors: Jianglei Chen, Yi Lin, Zhongjie Sun
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Molecular Medicine
Subjects:
Asporin
Osteocalcin
Osteopontin
Osteoblast
BMP2
Runx2
Online Access:https://doi.org/10.1186/s10020-023-00619-4

Internet

https://doi.org/10.1186/s10020-023-00619-4

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