Theophylline-encapsulated Nile Tilapia fish scale-based collagen nanoparticles effectively target the lungs of male Sprague–Dawley rats

Abstract Nile Tilapia fish scale collagen has high biodegradability, excellent biocompatibility, and low antigenicity. We assessed both the encapsulation efficiency of theophylline into Nile Tilapia fish scale-based collagen nanoparticles and their stability as a pulmonary drug delivery system in ma...

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Bibliographic Details
Main Authors: Mohammed Moustapha Anwar, Manal Aly Shalaby, Hesham Saeed, Haitham Mohammed Mostafa, Dalia Galal Hamouda, Howaida Nounou
Format: Article
Language:English
Published: Nature Portfolio 2022-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-08880-z