Accumulation of meningeal lymphocytes correlates with white matter lesion activity in progressive multiple sclerosis

Subpial cortical demyelination is an important component of multiple sclerosis (MS) pathology contributing to disease progression, yet mechanism(s) underlying its development remain unclear. Compartmentalized inflammation involving the meninges may drive this type of injury. Given recent findings id...

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Bibliographic Details
Main Authors: Shanzeh M. Ahmed, Nina L. Fransen, Hanane Touil, Iliana Michailidou, Inge Huitinga, Jennifer L. Gommerman, Amit Bar-Or, Valeria Ramaglia
Format: Article
Language:English
Published: American Society for Clinical investigation 2022-03-01
Series:JCI Insight
Subjects:
Online Access:https://doi.org/10.1172/jci.insight.151683