Bi-Allelic Mutations in Zebrafish <i>pank2</i> Gene Lead to Testicular Atrophy and Perturbed Behavior without Signs of Neurodegeneration

Bi-Allelic Mutations in Zebrafish <i>pank2</i> Gene Lead to Testicular Atrophy and Perturbed Behavior without Signs of Neurodegeneration

Coenzyme A (CoA) is an essential cofactor in all living organisms, being involved in a large number of chemical reactions. Sequence variations in pantothenate kinase 2 (PANK2), the first enzyme of CoA biosynthesis, are found in patients affected by Pantothenate Kinase Associated Neurodegeneration (P...

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Bibliographic Details
Main Authors: Luca Mignani, Daniela Zizioli, Deepak Khatri, Nicola Facchinello, Marco Schiavone, Giuseppe De Palma, Dario Finazzi
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:International Journal of Molecular Sciences
Subjects:
PANK2
Coenzyme A
neurodegeneration
zebrafish
iron
Online Access:https://www.mdpi.com/1422-0067/23/21/12914

Internet

https://www.mdpi.com/1422-0067/23/21/12914

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