14-3-3η Promotes Invadosome Formation via the FOXO3–Snail Axis in Rheumatoid Arthritis Fibroblast-like Synoviocytes

14-3-3η Promotes Invadosome Formation via the FOXO3–Snail Axis in Rheumatoid Arthritis Fibroblast-like Synoviocytes

Erosive destruction of joint structures is a critical event in the progression of rheumatoid arthritis (RA), in which fibroblast-like synoviocytes (FLS) are the primary effectors. We previously reported that the ability of RA FLS to degrade extracellular matrix (ECM) components depends on the format...

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Bibliographic Details
Main Authors: Maleck Kadiri, Martine Charbonneau, Catherine Lalanne, Kelly Harper, Frédéric Balg, Anthony Marotta, Claire M. Dubois
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:International Journal of Molecular Sciences
Subjects:
14-3-3η
FOXO3
Snail
rheumatoid arthritis
fibroblast-like synoviocytes
invadosome
Online Access:https://www.mdpi.com/1422-0067/23/1/123

Internet

https://www.mdpi.com/1422-0067/23/1/123

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