Novel Evolutionary Engineering Approach to Alter Substrate Specificity of Disaccharide Transporter Mal11 in <i>Saccharomyces cerevisiae</i>

A major challenge in the research of transport proteins is to understand how single amino acid residues contribute to their structure and biological function. Amino acid substitutions that result in a selective advantage in adaptive laboratory evolution experiments can provide valuable hints at thei...

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Bibliographic Details
Main Authors: Sophie Claire de Valk, Robert Mans
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Journal of Fungi
Subjects:
Online Access:https://www.mdpi.com/2309-608X/8/4/358