Mirror proteases of Ac-Trypsin and Ac-LysargiNase precisely improve novel event identifications in Mycolicibacterium smegmatis MC2 155 by proteogenomic analysis
Accurate identification of novel peptides remains challenging because of the lack of evaluation criteria in large-scale proteogenomic studies. Mirror proteases of trypsin and lysargiNase can generate complementary b/y ion series, providing the opportunity to efficiently assess authentic novel peptid...
Main Authors: | Songhao Jiang, Jiahui Shi, Yanchang Li, Zhenpeng Zhang, Lei Chang, Guibin Wang, Wenhui Wu, Liyan Yu, Erhei Dai, Lixia Zhang, Zhitang Lyu, Ping Xu, Yao Zhang |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-10-01
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Series: | Frontiers in Microbiology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fmicb.2022.1015140/full |
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