Evaluation and Optimization of Prolonged Release Mucoadhesive Tablets of Dexamethasone for Wound Healing: In Vitro–In Vivo Profiling in Healthy Volunteers

Evaluation and Optimization of Prolonged Release Mucoadhesive Tablets of Dexamethasone for Wound Healing: In Vitro–In Vivo Profiling in Healthy Volunteers

The aim of the projected study was to design and develop a novel strategy for evaluating the mucoadhesive potential of polymeric tablets of dexamethasone (DXM) for local delivery against wounds. Therefore, formulations (Q1–Q7) were synthesized via direct compression method by varying the concentrati...

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Bibliographic Details
Main Authors: Qurrat ul Ain Javed, Muhammad Ali Syed, Rabia Arshad, Abbas Rahdar, Muhammad Irfan, Syed Atif Raza, Gul Shahnaz, Sana Hanif, Ana M. Díez-Pascual
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Pharmaceutics
Subjects:
dexamethasone
hemostatic
wound healing
salivary pharmacokinetic
mucoadhesive buccal tablet
in vitro–in vivo
Online Access:https://www.mdpi.com/1999-4923/14/4/807

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https://www.mdpi.com/1999-4923/14/4/807

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