A Model for p38MAPK-Induced Astrocyte Senescence.

Experimental evidence indicates that aging leads to accumulation of senescent cells in tissues and they develop a secretory phenotype (also known as SASP, for senescence-associated secretory phenotype) that can contribute to chronic inflammation and diseases. Recent results have showed that markers...

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Bibliographic Details
Main Authors: José C M Mombach, Bruno Vendrusculo, Cristhian A Bugs
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0125217