The development of therapeutic antibodies that neutralize homologous and heterologous genotypes of dengue virus type 1.

The development of therapeutic antibodies that neutralize homologous and heterologous genotypes of dengue virus type 1.

Antibody protection against flaviviruses is associated with the development of neutralizing antibodies against the viral envelope (E) protein. Prior studies with West Nile virus (WNV) identified therapeutic mouse and human monoclonal antibodies (MAbs) that recognized epitopes on domain III (DIII) of...

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Main Authors: Bimmi Shrestha, James D Brien, Soila Sukupolvi-Petty, S Kyle Austin, Melissa A Edeling, Taekyung Kim, Katie M O'Brien, Christopher A Nelson, Syd Johnson, Daved H Fremont, Michael S Diamond
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-04-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20369024/pdf/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20369024/pdf/?tool=EBI

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