Biophysical characterization and a roadmap towards the NMR solution structure of G0S2, a key enzyme in non-alcoholic fatty liver disease.

In the United States non-alcoholic fatty liver disease (NAFLD) is the most common form of chronic liver disease, affecting an estimated 80 to 100 million people. It occurs in every age group, but predominantly in people with risk factors such as obesity and type 2 diabetes. NAFLD is marked by fat ac...

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Bibliographic Details
Main Authors: Michael W Moran, Elizabeth P Ramirez, James D Zook, Alicia M Saarinen, Bobby Baravati, Matthew R Goode, Vasiliki Laloudakis, Emily K Kaschner, Tien L Olson, Felicia M Craciunescu, Debra T Hansen, Jun Liu, Petra Fromme
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0249164