The secret lives of cancer cell lines

The extent of genetic and epigenetic diversity between and within patient tumors is being mapped in ever more detail. It is clear that cancer is an evolutionary process in which tumor cell intrinsic and extrinsic forces shape clonal selection. The pre-clinical oncology pipeline uses model systems of...

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Bibliographic Details
Main Authors: Robert E. Hynds, Elina Vladimirou, Sam. M. Janes
Format: Article
Language:English
Published: The Company of Biologists 2018-11-01
Series:Disease Models & Mechanisms
Subjects:
Online Access:http://dmm.biologists.org/content/11/11/dmm037366