Role of tumour associated macrophages in tumour angiogenesis and lymphangiogenesis

Role of tumour associated macrophages in tumour angiogenesis and lymphangiogenesis

Tumour angiogenesis is an essential process for supplying rapidly growing malignant tissues with essential nutrients and oxygen. An angiogenic switch allows tumour cells to survive and grow, and provides them access to vasculature resulting in metastatic disease. Monocyte-derived macrophages recruit...

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Bibliographic Details
Main Authors: Julia eKzhyshkowska, Vladimir eRiabov, Alexandru eGudima, Nan eWang, Alexander eOrekhov, Amanda eMickley
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-03-01
Series:Frontiers in Physiology
Subjects:
Lymphangiogenesis
VEGF
Angiogenesis
tumour-associated macrophages
chitinase-like protein
TIE2 receptor
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00075/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00075/full

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